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Research Introduction

Aging alters both the regenerative capacity and functional integrity of the adult brain, and as a result steadily drives cognitive impairments and susceptibility to neurodegenerative disorders in healthy individuals. In fact, aging remains the single most predominant risk factor for dementia-related neurodegenerative diseases in the elderly, such as Alzheimer’s disease. Now considering the rate at which the human population is currently aging, it becomes critical to identify ways by which to maintain cognitive integrity by protecting against, or even counteracting, the effects of aging. Our lab will investigate the cellular and molecular mechanisms that contribute to brain aging, as well as those that promote the rejuvenation of the old brain. The ultimate goal of our work is to better understand how to ameliorate age-related cognitive dysfunction by harnessing the latent plasticity still remaining within the old brain.

Read more about Neuroimmunology and Brain Rejuvenation.